LncRNA MEG3 inhibits the progression of prostate cancer by modulating miR-9-5p/QKI-5axis
نویسندگان
چکیده
منابع مشابه
miR-539 inhibits prostate cancer progression by directly targeting SPAG5.
BACKGROUND We conducted multiple microarray datasets analyses from clinical and xenograft tumor tissues to search for disease progression-driving oncogenes in prostate cancer (PCa). Sperm-associated antigen 5 (SPAG5) attracted our attention. SPAG5 was recently identified as an oncogene participating in lung cancer and cervical cancer progression. However, the roles of SPAG5 in PCa progression r...
متن کاملThe lncRNA PCAT29 inhibits oncogenic phenotypes in prostate cancer.
UNLABELLED Long noncoding RNAs (lncRNA) have recently been associated with the development and progression of a variety of human cancers. However, to date, the interplay between known oncogenic or tumor-suppressive events and lncRNAs has not been well described. Here, the novel lncRNA, prostate cancer-associated transcript 29 (PCAT29), is characterized along with its relationship to the androge...
متن کاملmiR-195 Inhibits Tumor Progression by Targeting RPS6KB1 in Human Prostate Cancer.
PURPOSE To investigate the involvement of hsa-miRNA-195-5p (miR-195) in progression and prognosis of human prostate cancer. EXPERIMENTAL DESIGN qRT-PCR was performed to detect miR-195 expression in both prostate cancer cell lines and clinical tissue samples. Its clinical significance was statistically analyzed. The roles of miR-195 and its candidate target gene, ribosomal protein S6 kinase, 7...
متن کاملZNF367 Inhibits Cancer Progression and Is Targeted by miR-195
BACKGROUND Several members of the zinc finger protein family have been recently shown to have a role in cancer initiation and progression. Zinc finger protein 367 (ZNF367) is a member of the zinc finger protein family and is expressed in embryonic or fetal erythroid tissue but is absent in normal adult tissue. METHODOLOGY/PRINCIPAL FINDINGS We show that ZNF367 is overexpressed in adrenocortic...
متن کاملmiR-449a inhibits colorectal cancer progression by targeting SATB2
miR-449a has been reported to act as a tumor suppressor in several cancers, however, it is controversial whether it inhibits tumor growth in colorectal cancer. The mechanisms underlying its expression and functions in colorectal cancers are still largely unknown. SATB2 is a sensitive and specific marker for CRC diagnosis. However, the mechanisms by which the expression and functions of SATB2 ar...
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ژورنال
عنوان ژورنال: Journal of Cellular and Molecular Medicine
سال: 2018
ISSN: 1582-1838
DOI: 10.1111/jcmm.13658